µP

microPublication Biology

Irfana Muqbil1§ORCID logo, and Jordan D Johnson2

1Department of Natural Sciences, Lawrence Technological University, Southfield, MI USA

2Department of Biomedical Engineering, Lawrence Technological University, Southfield, MI USA

§Correspondence to: Irfana Muqbil (imuqbil@ltu.edu)

Abstract

Description

Methods

Extended Data

  • Description: Extended Data Figure 1. Two-dimensional interaction maps of prioritized compounds in the predicted binding regions of MuRF1 and Atrogin-1. (A–B) Predicted interactions of EM12-So2F with MuRF1 and Atrogin-1, respectively. (C–D) Predicted interactions of thalidomide with MuRF1 and Atrogin-1, respectively. The maps show interacting residues and interaction types: conventional hydrogen bonds (green dashed lines), van der Waals contacts (light green), π–sigma interactions (purple), and π–alkyl interactions (pink). These maps provide structural context for the predicted binding poses in Figure 1D–G.. Resource Type: Image. DOI: 10.22002/v1njh-67936

Acknowledgements

Conflicts of Interest

Funding

Author Contributions

  • Irfana Muqbil: Conceptualization, Supervision, Resources, Writing - original draft
  • Jordan D Johnson: Data curation, Formal analysis, Methodology, Visualization

Reviewed By

Anonymous

History

  • Received: 6/18/2026
  • Revision Received: 9/14/2026
  • Accepted: 9/29/2026
  • Published Online: 10/1/2026

Copyright

© 2026 by the authors. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International (CC BY 4.0) License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Citation

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The microPublication project is supported by

The National Institute of Health -- Grant #: 1U01LM012672-01

microPublication Biology:ISSN: 2578-9430