Caenorhabditis Intervention Testing Program: the anticonvulsant leviteracetam does not extend lifespan in nematodes.

Akella, Jyothi Shilpa; Onken, Brian D; Sedore, Christine A; Song, Yuhua; Achanta, Vijaya Madhuri; Walker, Monique; Xue, Jian; Guo, Suzhen; Coleman-Hulbert, Anna; Phillips, Patrick C; Lithgow, Gordon J; Driscoll, Monica

doi:10.17912/micropub.biology.001987

µP

microPublication Biology

Jyothi Shilpa Akella¹, Brian D Onken¹, Christine A Sedore², Yuhua Song¹, Vijaya Madhuri Achanta¹, Monique Walker¹, Jian Xue¹, Suzhen Guo¹, Anna Coleman-Hulbert², Patrick C Phillips², Gordon J Lithgow³, and Monica Driscoll¹^§

¹Department of Molecular Biology and Biochemistry, Rutgers University, Piscataway, New Jersey 08854, USA

²Institute of Ecology and Evolution, University of Oregon, Eugene, Oregon 97403, USA

³The Buck Institute for Research on Aging, Novato, California 94945, USA

^§Correspondence to: Monica Driscoll (driscoll@dls.rutgers.edu)

Abstract

Description

Methods

Reagents

Acknowledgements

Conflicts of Interest

Funding

Author Contributions

Jyothi Shilpa Akella: Writing - original draft, Writing - review & editing
Brian D Onken: Project administration, Writing - review & editing
Christine A Sedore: Data curation, Formal analysis, Visualization, Writing - review & editing
Yuhua Song: Investigation
Vijaya Madhuri Achanta: Investigation
Monique Walker: Investigation
Jian Xue: Investigation
Suzhen Guo: Investigation
Anna Coleman-Hulbert: Project administration
Patrick C Phillips: Funding acquisition, Methodology, Writing - review & editing
Gordon J Lithgow: Funding acquisition, Methodology, Writing - review & editing
Monica Driscoll: Funding acquisition, Methodology, Supervision, Writing - review & editing

Reviewed By

Anonymous

Nomenclature Validated By

Anonymous

Database Reference ID: WBPaper00069347

History

Received: 12/12/2025
Revision Received: 3/25/2026
Accepted: 3/30/2026
Published Online: 3/31/2026

References

Copyright

© 2026 by the authors. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International (CC BY 4.0) License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Citation

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The microPublication project is supported by

The National Institute of Health -- Grant #: 1U01LM012672-01

microPublication Biology:ISSN: 2578-9430